What is a common side effect of Codeine?

Codeine is an opioid analgesic that is commonly prescribed for pain relief. A significant side effect associated with the use of codeine is respiratory depression. This occurs because codeine, like other opioids, binds to specific receptors in the brain that regulate breathing. When these receptors are activated, the normal respiratory drive can be diminished, which can lead to decreased breathing rates and depth. This side effect is particularly concerning, especially in higher doses or when used in combination with other central nervous system depressants.

While nausea is also a potential side effect of codeine and can affect many individuals taking opioids, the risk of serious respiratory depression is a critical aspect of monitoring patients on codeine therapy. This makes understanding the respiratory depressant effects paramount in clinical settings. Headaches and insomnia, while possible side effects, are not as closely associated with codeine use as respiratory depression is, which reflects its importance in patient safety and effective pain management practices.