What is a serious adverse reaction associated with cephalosporins?

Anaphylaxis is a serious adverse reaction associated with cephalosporins due to their structural similarities to penicillins. This can lead to an immune response that triggers a severe allergic reaction, characterized by symptoms such as difficulty breathing, swelling of the face or throat, rapid heartbeat, and a drop in blood pressure. Anaphylaxis is a medical emergency that requires immediate treatment, often with epinephrine, as it can be life-threatening.

Other adverse reactions, such as dry mouth, rash, and insomnia, can occur with various medications, including cephalosporins, but they are generally less severe and do not pose an immediate threat to life. While rashes can be a part of allergic reactions, they do not carry the same level of urgency and risk as anaphylaxis. Therefore, understanding the nature and severity of these reactions is critical for anyone using or prescribing cephalosporin antibiotics.