What should penicillins be taken with to avoid decomposition?

The recommendation to take penicillins with a full glass of water is based on the stability and absorption of the medication in the gastrointestinal tract. Taking penicillins with plenty of water helps to dissolve the tablet or capsule and ensures that the drug is adequately absorbed into the bloodstream. Additionally, it helps to dilute the medication and reduce the potential for stomach irritation, which can sometimes occur with certain antibiotics.

While penicillins can be affected by the presence of food or other substances in the stomach, taking them with water is generally considered safe and effective. It promotes the optimal absorption of the medication, avoiding possible degradation that might occur in a more acidic environment or if there's not enough fluid to facilitate digestion. This approach supports the overall effectiveness of the medication while minimizing any adverse effects.

Food often influences the absorption of various medications, and with some antibiotics, taking them with food can be necessary. However, this isn't the case for penicillins, which are usually prescribed to be taken either on an empty stomach or with minimal food to ensure effective absorption. Taking them with acidic juices may increase the acidity in the stomach, which could potentially affect the stability of certain antibiotics, while taking them on an empty stomach may not provide adequate hydration or dilution needed