Which adverse reaction is associated with Digoxin?

Digoxin is a medication commonly used to treat various heart conditions, including atrial fibrillation and heart failure. One of the notable adverse reactions associated with Digoxin is bradycardia, which is a condition characterized by a slower than normal heart rate.

Bradycardia occurs because Digoxin increases the vagal tone on the heart, which leads to a reduction in heart rate. This effect can be beneficial for patients with certain heart rhythm disorders but can also pose risks, particularly if the heart rate becomes too slow. Monitoring heart rate in patients taking Digoxin is essential to ensure that it remains within a safe range.

In contrast, other options such as seizures, hyperkalemia, and constipation, while they may present in patients taking various medications, are not specifically linked to Digoxin in the same way bradycardia is. Seizures are more commonly associated with other drugs or conditions, hyperkalemia typically relates to kidney function or other medications, and constipation is a side effect seen with different types of medications rather than a direct effect of Digoxin. Thus, bradycardia is the most directly associated adverse reaction to Digoxin therapy.