Which of the following side effects is commonly associated with the use of Aminoglycosides?

Aminoglycosides are a class of antibiotics that are primarily used to treat severe infections caused by gram-negative bacteria. One of the well-known side effects associated with aminoglycoside use is nephrotoxicity, which refers to damage to the kidneys. This side effect occurs because aminoglycosides can accumulate in the renal tissues, leading to impairments in kidney function. Monitoring kidney function through regular blood tests is often necessary during treatment to manage and mitigate this risk.

The other options listed do not have a strong association with aminoglycosides. Visual disturbances, while they can occur with some medications, are not commonly linked to this class of antibiotics. Flatulence and diarrhea are more frequently associated with other types of antibiotics, particularly those that disrupt gut flora. These gastrointestinal reactions are not characteristic of aminoglycosides, which tend to be administered in a hospital setting for more severe infections and are often given via injection rather than orally. Thus, the risk of nephrotoxicity in the context of aminoglycoside use stands out as the primary concern in this case.